Product image of Xifaxan 550 (Rifaximin) 550mg Tablet supplied by GNH India

Xifaxan 550

Active Ingredient:
Rifaximin
Form:
Tablet
Brand:
XIFAXAN
Origin:
Switzerland

Xifaxan 550 (Rifaximin Tablet) 550mg

Rifaximin, the active ingredient in Xifaxan 550, is a rifamycin antibiotic presented as a 550mg tablet for oral use. It is used to reduce the recurrence of overt hepatic encephalopathy in adults with liver disease and to treat travelers' diarrhea. GNH India supplies Xifaxan 550 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Xifaxan 550 is specifically designed to target and reduce harmful bacteria in the gut, thereby protecting the brain from bacterial toxins in patients with severe liver conditions. This medication is available by prescription and is known for its efficacy in managing specific gastrointestinal and liver-related conditions.

Strength

550mg

Pack Size

56s

Storage

Below 25°C

Manufacturer / TM Owner

Alfasigma

1
Pack/s
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Indications & Clinical Uses

Xifaxan 550 is primarily used to manage conditions related to gastrointestinal and liver health. It is indicated for the following:

  • Hepatic Encephalopathy: Reduces the recurrence of overt hepatic encephalopathy in adults with liver disease.
  • Travelers' Diarrhea: Treats diarrhea caused by non-invasive strains of Escherichia coli in travelers.
  • Irritable Bowel Syndrome with Diarrhea (IBS-D): Manages symptoms of IBS-D by reducing bacterial overgrowth in the gut.

How It Works

  • Rifaximin works by inhibiting bacterial RNA synthesis. It binds to the beta-subunit of DNA-dependent RNA polymerase, which prevents bacteria from producing essential proteins needed for their growth and replication. This action helps to reduce the number of harmful bacteria in the gut, thereby alleviating symptoms associated with gastrointestinal and liver conditions.

Side Effects

Xifaxan 550 may cause various side effects, ranging from common to serious. Common Side Effects:

  • Nausea
  • Headache
  • Abdominal pain
  • Dizziness
  • Vomiting

Serious or Rare Side Effects

  • Severe diarrhea, which may occur even after treatment has ended
  • Allergic reactions, including skin rashes, blisters, or swelling
  • Liver problems, which may require immediate medical attention
  • Clostridium difficile-associated diarrhea, a serious condition that can occur after antibiotic use

Precautions & Warnings

  • When using Xifaxan 550, certain precautions should be observed. Avoid taking this medication if you are allergic to rifaximin or any of its components. Inform your healthcare provider if you have a history of severe liver disease or if you are pregnant or breastfeeding. Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Xifaxan 550 may interact with other medications, which can affect its efficacy or increase the risk of side effects. Major Interactions (Avoid):

  • P-gp inhibitors: May increase the concentration of rifaximin in the blood, leading to potential toxicity.
  • Cytochrome P450 inhibitors: Can alter the metabolism of rifaximin, affecting its effectiveness.

Moderate Interactions (Monitor Closely)

  • Antidiarrheal medications: May reduce the effectiveness of Xifaxan 550 in treating diarrhea.
  • Probiotics: May interfere with the action of rifaximin, potentially reducing its efficacy.

Frequently Asked Questions

Xifaxan 550 is used to reduce the recurrence of overt hepatic encephalopathy in adults with liver disease and to treat travelers' diarrhea caused by non-invasive strains of Escherichia coli. It is also used to manage symptoms of irritable bowel syndrome with diarrhea (IBS-D) by reducing bacterial overgrowth in the gut.

Rifaximin works by inhibiting bacterial RNA synthesis. It binds to the beta-subunit of DNA-dependent RNA polymerase, which prevents bacteria from producing essential proteins needed for their growth and replication. This action helps to reduce the number of harmful bacteria in the gut, thereby alleviating symptoms associated with gastrointestinal and liver conditions.

The usual dose of Xifaxan 550 is determined by a healthcare provider based on the patient's condition and medical history. It is typically taken as prescribed, and patients should follow their doctor's instructions for the best results.

The safety of Xifaxan 550 during pregnancy or breastfeeding has not been fully established. Patients should consult their healthcare provider before taking this medication if they are pregnant or breastfeeding to discuss the potential risks and benefits.

To order Xifaxan 550 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.

Xifaxan 550 is a non-systemic antibiotic, meaning it primarily acts in the gut and is not absorbed into the bloodstream. This makes it different from many other antibiotics that are systemic and can have broader effects on the body. Its targeted action reduces the risk of systemic side effects.

Xifaxan 550 should be stored below 25°C, kept in the original pack, and protected from moisture. Proper storage ensures the medication remains effective and safe for use. Always follow the storage instructions provided with the medication.

Xifaxan 550 is administered orally, typically as a tablet. It can be taken with or without food, as directed by a healthcare provider. Patients should follow their doctor's instructions for the best results and to ensure the medication is effective.

The most serious risks to watch for with Xifaxan 550 include severe diarrhea, which may occur even after treatment has ended, and allergic reactions, including skin rashes, blisters, or swelling. Patients should seek immediate medical attention if they experience any of these symptoms.

Patients who are allergic to rifaximin or any of its components should not use Xifaxan 550. Additionally, patients with severe liver disease or those who are pregnant or breastfeeding should consult their healthcare provider before taking this medication to discuss the potential risks and benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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