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Betamethasone Valerate (Betamethasone Valerate)

Trade Name : Betamethasone Valerate

NuCare Pharmaceuticals,Inc.

CREAM

Strength 1.2 mg/g

BETAMETHASONE VALERATE Corticosteroid [EPC],Corticosteroid Hormone Receptor Agonists [MoA]

Delivery Process

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Product information is meant for

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Betamethasone Valerate (Betamethasone Valerate) which is also known as Betamethasone Valerate and Manufactured by NuCare Pharmaceuticals,Inc.. It is available in strength of 1.2 mg/g per ml. Read more

Betamethasone Valerate (Betamethasone Valerate) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Betamethasone Valerate Cream and Betamethasone Valerate Ointment contain Betamethasone Valerate USP (9-Fluoro-11u03b2,17,21-trihydroxy-16u03b2-methylpregna-1,4-diene-3,20-dione 17-valerate); its empirical formula is Cn n n Hn n n FOn n n ; its molecular weight is 476n n n 59 (CAS Registry Number 2152-44-5); its structural formula is:n nn
  • Each gram of the 0n n n 1% cream contains 1n n n 2 mg betamethasone valerate (equivalent to 1n n n 0 mg betamethasone) in a hydrophilic cream base consisting of purified water, mineral oil, white petrolatum, polyethylene glycol 1000 monocetyl ether, cetostearyl alcohol, monobasic sodium phosphate, phosphoric acid or sodium hydroxide and 4-chloro-m-cresol as a preservative. Each gram of the 0n n n 1% ointment contains 1n n n 2 mg betamethasone valerate (equivalent to 1n n n 0 mg betamethasone) in an ointment base consisting of mineral oil, white petrolatum and hydrogenated lanolin.n nn
  • Topical corticosteroids share anti-inflammatory, anti-pruritic and vasoconstrictive actions. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.
  • The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings. Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses (See n n n ). Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.n nn
  • Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
  • Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
  • No data
  • The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning, Itching, Irritation, Dryness, Folliculitis, Hypertrichosis, Acneiform eruptions, Hypopigmentation, Perioral dermatitis, allergic contact dermatitis, Maceration of the skin, Secondary infection, Skin Atrophy, Striae and Miliaria.
  • Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects (see n n n ).n nn
  • Betamethasone Valerate Cream 0n n n 1% and Betamethasone Valerate Ointment 0n n n 1% are generally applied to the affected area as a thin film one to three times daily depending on the severity of the condition. Dosage once or twice a day is often effective. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.n nn
  • Betamethasone Valerate Cream USP, 0 n 1% is supplied in:n
  • NDC 66267-984-15 Box of 15g
  • Betamethasone Valerate Ointment USP, 0 n 1% is supplied in:n
  • Manufactured by
  • Actavis Mid Atlantic LLC
  • 1877 Kawai Road
  • Lincolnton, NC 28092 USA
  • FORM NO. 0370/0371
  • VC2795
  • Rev. 2/06
  • No data

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Comparator Sourcing for Clinical Trials

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Validated Cold Chain Shipment

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