Butorphanol Tartrate (Butorphanol Tartrate)

Trade Name : Butorphanol Tartrate

West-Ward Pharmaceuticals Corp

INJECTION, SOLUTION

Strength 1 mg/mL

BUTORPHANOL TARTRATE Competitive Opioid Antagonists [MoA],Opioid Agonist/Antagonist [EPC],Partial Opioid Agonists [MoA]

Delivery Process

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Product information is meant for

Wholesalers Suppliers Exporters Doctors MOH Tender Supplies Hospitals Brand CROs Comparator Supplies Generic Cooperate Sourcing Individual Patients Indian Institutional Buyers

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Butorphanol Tartrate (Butorphanol Tartrate) which is also known as Butorphanol Tartrate and Manufactured by West-Ward Pharmaceuticals Corp. It is available in strength of 1 mg/mL per ml. Read more

Butorphanol Tartrate (Butorphanol Tartrate) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

Inquire directly from our website and get 5% off on any medicine!

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

Read more
  • No data
  • CIV
  • Rx Onlyu00a0
  • Addiction, Abuse, and Misuse
  • Butorphanol Tartrate Injection exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patientu2019s risk prior to prescribing Butorphanol Tartrate Injection, and monitor all patients regularly for the development of these behaviors or conditions [see ].
  • Life-Threatening Respiratory Depression
  • Serious, life-threatening, or fatal respiratory depression may occur with use of Butorphanol Tartrate Injection. Monitor for respiratory depression, especially during initiation of Butorphanol Tartrate Injection or following a dose increase [see ].
  • Neonatal Opioid Withdrawal Syndrome
  • Prolonged use of butorphanol Tartrate Injection during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available [see ].
  • Risks From Concomitant Use With Benzodiazepines Or Other CNS Depressantsn- u00a0
  • Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death [see , ].
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  • Butorphanol tartrate is an opioid agonist-antagonist of the phenanthrene series. The chemical name is (-)-17-(cyclobutylmethyl) morphinan-3,14-diol [S-(R*,R*)]-2,3-dihydroxybutanedioate(1:1)(salt). The molecular formula is CHNO,CHO, which corresponds to a molecular weight of 477.55 and the following structural formula:
  • Butorphanol tartrate is a white crystalline substance. The dose is expressed as the tartrate salt. One milligram of the salt is equivalent to 0.68 mg of the free base. The n-octanol/aqueous buffer partition coefficient of butorphanol is 180:1 at pH 7.5.
  • Butorphanol Tartrate Injection, USPu00a0is a sterile, nonpyrogenic, parenteral, aqueous solution of butorphanol tartrate for intravenous or intramuscular administration. Each milliliter (mL) of solution contains, butorphanol tartrate 1 or 2 mg,u00a03.3 mg of citric acid, 6.4 mg sodium citrate, and 6.4 mg sodium chloride, and 0.1 mg benzethonium chloride (in multiple dose vial only) as a preservative.
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  • Butorphanol Tartrate Injection is indicated:
  • Limitations of Use
  • Because of the risks of addiction, abuse, and misuse, with opioids, even at recommended doses [see ], reserve Butorphanol Tartrate Injection for use in patients for whom alternative treatment options [e.g. non-opioid analgesics]
  • Butorphanol Tartrate Injection is contraindicated in:
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  • Butorphanol Tartrate Injection is supplied as follows:
  • 1 mg/mL, 1 mL vial, 10 vials per carton (NDC 0143-9864-10)
  • 2 mg/mL, 1 mL vial, 10 vials per carton (NDC 0143-9867-10)
  • 4 mg/2 mL, 2 mL vial, 10 vials per carton (NDC 0143-9863-10)
  • 20 mg/10 mL, 10 mL vial, 10 vials per carton (NDC 0143-9866-10)
  • Store at 20u00ba-25u00b0C (68u00ba-77u00b0F) [See USP Controlled Room Temperature].
  • Protect from light. Discard unused portion. Retain in carton until time of use.
  • Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
  • Manufactured by:n
  • Distributed by:n
  • Revised: November 2016
  • PIN199-WES/4
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