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Clindamycin Phosphate (Cleocin T)

Trade Name : Cleocin T

Pharmacia and Upjohn Company LLC

SOLUTION

Strength 10 mg/mL

CLINDAMYCIN PHOSPHATE Decreased Sebaceous Gland Activity [PE],Lincosamide Antibacterial [EPC],Lincosamides [CS]

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Product information is meant for

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Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Clindamycin Phosphate (Cleocin T) which is also known as Cleocin T and Manufactured by Pharmacia and Upjohn Company LLC. It is available in strength of 10 mg/mL per ml. Read more

Clindamycin Phosphate (Cleocin T) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • For External Use
  • CLEOCIN T Topical Solution and CLEOCIN T Topical Lotion contain clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per milliliter. CLEOCIN T Topical Gel contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per gram. Each CLEOCIN T Topical Solution pledget applicator contains approximately 1 mL of topical solution.
  • Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.
  • The solution contains isopropyl alcohol 50% v/v, propylene glycol, and water.
  • The gel contains allantoin, carbomer 934P, methylparaben, polyethylene glycol 400, propylene glycol, sodium hydroxide, and purified water.
  • The lotion contains cetostearyl alcohol (2.5%); glycerin; glyceryl stearate SE (with potassium monostearate); isostearyl alcohol (2.5%); methylparaben (0.3%); sodium lauroyl sarcosinate; stearic acid; and purified water.
  • The structural formula is represented below:
  • The chemical name for clindamycin phosphate is Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl--4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L--u03b1-D--octopyranoside 2-(dihydrogen phosphate).
  • No data
  • CLEOCIN T Topical Solution, CLEOCIN T Topical Gel and CLEOCIN T Topical Lotion are indicated in the treatment of acne vulgaris. In view of the potential for diarrhea, bloody diarrhea and pseudomembranous colitis, the physician should consider whether other agents are more appropriate (see , and ).
  • CLEOCIN T Topical Solution, CLEOCIN T Topical Gel and CLEOCIN T Topical Lotion are contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis.
  • Orally and parenterally administered clindamycin has been associated with severe colitis which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
  • Studies indicate a toxin(s) produced by clostridia is one primary cause of antibiotic-associated colitis. The colitis is usually characterized by severe persistent diarrhea and severe abdominal cramps and may be associated with the passage of blood and mucus. Endoscopic examination may reveal pseudomembranous colitis. n- Stool culture for n- Clostridium difficilen- and stool assay for n- C. difficilen- toxin may be helpful diagnostically.
  • When significant diarrhea occurs, the drug should be discontinued. Large bowel endoscopy should be considered to establish a definitive diagnosis in cases of severe diarrhea.
  • Antiperistaltic agents such as opiates and diphenoxylate with atropine may prolong and/or worsen the condition. Vancomycin has been found to be effective in the treatment of antibiotic-associated pseudomembranous colitis produced by . The usual adult dosage is 500 milligrams to 2 grams of vancomycin orally per day in three to four divided doses administered for 7 to 10 days. . If both a resin and vancomycin are to be administered concurrently, it may be advisable to separate the time of administration of each drug.
  • Diarrhea, colitis, and pseudomembranous colitis have been observed to begin up to several weeks following cessation of oral and parenteral therapy with clindamycin.
  • No data
  • In 18 clinical studies of various formulations of CLEOCIN T using placebo vehicle and/or active comparator drugs as controls, patients experienced a number of treatment emergent adverse dermatologic events [see below].
  • Orally and parenterally administered clindamycin has been associated with severe colitis which may end fatally.
  • Cases of diarrhea, bloody diarrhea and colitis (including pseudomembranous colitis) have been reported as adverse reactions in patients treated with oral and parenteral formulations of clindamycin and rarely with topical clindamycin (see ).
  • Abdominal pain, gastrointestinal disturbances, gram-negative folliculitis, eye pain and contact dermatitis have also been reported in association with the use of topical formulations of clindamycin.
  • Topically applied CLEOCIN T can be absorbed in sufficient amounts to produce systemic effects (see ).
  • Apply a thin film of CLEOCIN T Topical Solution, CLEOCIN T Topical Lotion, CLEOCIN T Topical Gel, or use a CLEOCIN T Topical Solution pledget for the application of CLEOCIN T twice daily to affected area. More than one pledget may be used. Each pledget should be used only once and then be discarded.
  • Lotion: Shake well immediately before using.
  • Pledget: Remove pledget from foil just before use. Do not use if the seal is broken. Discard after single use.
  • Keep all liquid dosage forms in containers tightly closed.
  • CLEOCIN T Topical Solution containing clindamycin phosphate equivalent to 10 mg clindamycin per milliliter is available in the following sizes:
  • 30 mL
  • 60 mL
  • Carton of 60 single-use pledget
  • CLEOCIN T Topical Gel containing clindamycin phosphate equivalent to 10 mg clindamycin per gram is available in the following sizes:
  • 60 gram
  • 30 gram
  • CLEOCIN T Topical Lotion containing clindamycin phosphate equivalent to 10 mg clindamycin per milliliter is available in the following size:
  • 60 mL
  • Store at controlled room temperature 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F) [see USP].
  • Protect from freezing.
  • Rx only
  • This product's label may have been updated. For current full prescribing information, please visit www.pfizer.com.
  • LAB-0042-10.0Revised 12/2019
  • Pfizer
  • NDC 0009-3116-01
  • Cleocin T
  • 1%*
  • Solution
  • 30 mL
  • Rx only
  • Pfizer
  • NDC 0009-3116-01
  • Cleocin T
  • 1%*
  • Solution
  • 30 mLn n
  • Pfizer
  • NDC 0009-3116-14
  • Cleocin T
  • 1%*
  • Pledget
  • 1 Pledget
  • Distributed byPharmacia & Upjohn CoDivision of Pfizer Inc, NY, NY 10017MADE IN CHINA
  • Rx only
  • NDC 0009-3116-14
  • Pfizern- Cleocin Tn- 1%*
  • Pledget
  • 60 Pledgetsn n
  • Pfizer NDC 0009-3329-01
  • Cleocin Tn clindamycinphosphatetopical lotion
  • 1%*
  • For topical use only
  • 60 mL Rx only
  • Pfizer NDC 0009-3329-01
  • Cleocin Tn clindamycinphosphatetopical lotion
  • 1%*
  • For topical use only
  • 60 mL Rx only
  • NDC 0009-3331-01
  • 60 gram
  • Rx only
  • Cleocin T
  • For topical use only
  • 1%*
  • Store at controlled room temperature 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F)[see USP]. Protect from freezing.n- DOSAGE AND USE:
  • Pfizern- Distributed byn- Pharmacia & Upjohn Co
  • NDC 0009-3331-01
  • Pfizer
  • Cleocin Tn 1%*
  • clindamycin phosphate topical gel
  • For topical use only
  • 60 gram Rx only
  • NDC 0009-3331-02
  • 30 gram
  • Rx only
  • Cleocin T
  • For topical use only
  • 1%*
  • Store at controlled room temperature 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F)[see USP]. Protect from freezing.n- DOSAGE AND USE:
  • Pfizern- Distributed byn- Pharmacia & Upjohn Co
  • NDC 0009-3331-02
  • Pfizern- Cleocin Tn- 1%*
  • For topical use only
  • 30 gramn n

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