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Cyproheptadine Hydrochloride (Cyproheptadine Hydrochloride)

Trade Name : Cyproheptadine Hydrochloride

VistaPharm, Inc.

SOLUTION

Strength 2 mg/5mL

CYPROHEPTADINE

Delivery Process

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Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Cyproheptadine Hydrochloride (Cyproheptadine Hydrochloride) which is also known as Cyproheptadine Hydrochloride and Manufactured by VistaPharm, Inc.. It is available in strength of 2 mg/5mL per ml. Read more

Cyproheptadine Hydrochloride (Cyproheptadine Hydrochloride) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Each 5 mL (one teaspoonful) contains: Cyproheptadine Hydrochloride 2 mg
  • Inactive Ingredients:
  • Cyproheptadine HCl is an antihistaminic and antiserotonergic agent. Cyproheptadine hydrochloride is a white to slightly yellowish, crystalline solid, with a molecular weight of 350.89, which is slightly soluble in water, freely soluble in methanol, sparingly soluble in ethanol, soluble in chloroform and practically insoluble in ether. It is the sesquihydrate of 4-(5H-dibenzo[a,d] cyclohepten-5-ylidene)-1- methylpiperidine hydrochloride. The molecular formula of the anhydrous salt is CHNu2022HCl and the structural formula of the anhydrous salt is:
  • Cyproheptadine is a serotonin and histamine antagonist with anticholinergic and sedative effects. Antiserotonin and antihistamine drugs appear to compete with serotonin and histamine, respectively, for receptor sites.
  • Pharmacokinetics and Metabolism:
  • Perennial and seasonal allergic rhinitis
  • Vasomotor rhinitis
  • Allergic conjunctivitis due to inhalant allergens and foods
  • Mild, uncomplicated allergic skin manifestations of urticaria and angioedema
  • Amelioration of allergic reactions to blood or plasma
  • Cold urticaria
  • Dermatographism
  • As therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.n
  • Newborn or Premature Infants:
  • Nursing Mothers:
  • Other Conditions:
  • Hypersensitivity to cyproheptadine and other drugs of similar chemical structure
  • Monoamine oxidase inhibitor therapy (see Drug Interactions)
  • Angle-closure glaucoma
  • Stenosing peptic ulcer
  • Symptomatic prostatic hypertrophy
  • Bladder neck obstruction
  • Pyloroduodenal obstruction
  • Elderly, debilitated patients
  • Children:
  • Antihistamines may diminish mental alertness; conversely, particularly in the young child, they may occasionally produce excitation
  • CNS Depressants:
  • Activities Requiring Mental Alertness:
  • Antihistamines are more likely to cause dizziness, sedation and hypotension in elderly patients.
  • No data
  • Adverse reactions which have been reported with the use of antihistamines are as follows:
  • Central Nervous System:
  • Integumentary:
  • Special Senses:
  • Cardiovascular:
  • Hematologic:
  • Digestive System:
  • Genitourinary:
  • Respiratory:
  • Miscellaneous:
  • Antihistamine overdosage reactions may vary from central nervous system depression to stimulation especially in children. Also, atropine-like signs and symptoms (dry mouth; fixed, dilated pupils; flushing, etc.) as well as gastrointestinal symptoms may occur.
  • If vomiting has not occurred spontaneously, the patient should be induced to vomit with syrup of ipecac.
  • If the patient is unable to vomit, perform gastric lavage followed by activated charcoal. Isotonic or 1/2 isotonic saline is the lavage of choice. Precautions against aspiration must be taken especially in infants and children. When life-threatening CNS signs and symptoms are present, intravenous physostigmine salicylate may be considered. Dosage and frequency of administration are dependent on age, clinical response and recurrence after response. (See package circulars for physostigmine products.)
  • Saline cathartics, as milk of magnesia, by osmosis draw water into the bowel and, therefore, are valuable for their action in rapid dilution of bowel content.
  • Stimulants should not be used. Vasopressors may be used to treat hypotension.
  • The oral LD of cyproheptadine is 123 mg/kg, and 295 mg/kg in the mouse and rat, respectively.
  • DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO THE NEEDS AND THE RESPONSE OF THE PATIENT.
  • Each 5 mL of Cyproheptadine Hydrochloride Oral Solution contains 2 mg of Cyproheptadine hydrochloride.
  • Although intended primarily for administration to children, the oral solution is also used for administration to adults who cannot swallow tablets.
  • Children:
  • Age 2 to 6 years:
  • Age 7 to 14 years:
  • Adults:
  • Cyproheptadine Hydrochloride Oral Solution, USP, 2 mg/5 mL in a yellow, peppermint-flavored vehicle, is supplied in a pint (473 mL) container.
  • Store at 20u00b0-25u00b0C (68u00b0-77u00b0F) excursion permitted to 15u00b0-30u00b0C (59u00b0-86u00b0F) [See USP Controlled Room Temperature].
  • Dispense in a tight, light-resistant container as defined in the USP.
  • NDC # 66689-333-16
  • Manufactured for:
  • VistaPharm, Inc.
  • Largo, FL 33771 USA
  • Questions of Comments?
  • Call 1-888-655-1505
  • VP2260
  • Issue Date: 07/2018
  • VistaPharm
  • NDC 66689-333-16
  • Cyproheptadine
  • Hydrochloride
  • Oral Solution, USP
  • 2 mg/5 mL
  • 473 mL (ONE PINT)
  • Rx Only
  • u00a0

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