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Fluocinolone Acetonide (Capex)

Trade Name : Capex

Galderma Laboratories, L.P.

KIT

Strength

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Fluocinolone Acetonide (Capex) which is also known as Capex and Manufactured by Galderma Laboratories, L.P.. It is available in strength of per ml. Read more

Fluocinolone Acetonide (Capex) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Capex Shampoo 0.01% is supplied as a shampoo formulation with a 12 mg fluocinolone acetonide capsule which is emptied into the shampoo base by the pharmacist at the time of dispensing. After mixing, Capex Shampoo contains fluocinolone acetonide(6u03b1,9-Difluoro-11u03b2,16u03b1, 17,21-tetrahydroxypregna-1,4-diene-3, 20-dione cyclic 16,17-acetal with acetone), a synthetic fluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as an anti-inflammatory and antipruritic agents.
  • Chemically, Capex Shampoo mixture is CHFO. It has the following structural formula:
  • Fluocinolone acetonide in Capex Shampoo has the molecular weight of 452.50. It is a white crystalline powder that is odorless, stable in light and melts at 270u00b0F with decomposition; soluble in alcohol, acetone and methanol; slightly soluble in chloroform; insoluble in water.
  • Each fluocinolone capsule contains 12 mg of fluocinolone acetonide, 548 mg of dibasic calcium phosphate dihydrate USP, and 240 mg of talc USP. The shampoo base contains aluminum acetate dibasic, benzalkonium chloride solution, boric acid, citric acid anhydrous, cocamido-ether-sulfate complex, cocoamine oxide, lauramide DEA, magnesium aluminum silicate, methylparaben, oat flour, propylene glycol, propylparaben, purified water, and fragrances, with D&C Yellow #10 and FD&C Blue #1 as coloring.
  • Like other topical corticosteroids, fluocinolone acetonide has anti-inflammatory, antipruritic and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However corticosteroids are thought to act by the induction of phospholipase A inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A.
  • Pharmacokinetics:
  • Capex Shampoo is in the low to medium range of potency as compared with other topical corticosteroids.
  • In vehicle-controlled studies for the treatment of seborrheic dermatitis of the scalp, after 14 days of treatment, 84% of patients on active treatment and 29% of patients on the drug vehicle had cleared or markedly improved.
  • Capex Shampoo is a low to medium potency corticosteroid indicated for the treatment of seborrheic dermatitis of the scalp. This product has not been proven to be effective in other corticosteroid-responsive dermatoses.
  • Capex Shampoo is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
  • No data
  • The following local adverse reactions have been reported infrequently with topical corticosteroids. They may occur more frequently with the use of occlusive dressings, especially with higher potency corticosteroids. These reactions are listed in an approximate decreasing order of occurrence: dryness, folliculitis, acneiform eruptions, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae, miliaria, burning, itching, irritation and hypopigmentation.
  • Topically applied Capex Shampoo can be absorbed in sufficient amounts to produce systemic effects (See ).
  • The pharmacist must empty the contents of the enclosed capsule into the shampoo base prior to dispensing to the patient. This product should be shaken well prior to use. No more than approximately one (1) ounce of the medicated shampoo should be applied to the scalp area once daily, worked into a lather and allowed to remain on the scalp for approximately 5 minutes. The hair and scalp should then be rinsed thoroughly with water.
  • Capex Shampoo is supplied as a two component package: a capsule which contains the active component fluocinolone acetonide, and a separate package of liquid shampoo. The pharmacist must mix the content of the capsule into the base at the time of dispensing. Capex Shampoo is dispensed to the patient in a 6 ounce bottle.
  • Shake well before using.
  • Store at controlled room temperature 68u00b0 - 77u00b0F (20u00b0 - 25u00b0C) with excursions permitted between 59u00b0 - 86u00b0F (15u00b0 - 30u00b0C) in tightly closed containers.
  • Marketed by:
  • GALDERMA LABORATORIES, L.P.
  • Fort Worth, Texas 76177 USA
  • Made in Canada.
  • P52306-3
  • GALDERMA is a registered trademark.
  • Revised: December 2015
  • Capex (kap-eks) Shampoo(fluocinolone acetonide)Topical Shampoo, 0.01%
  • ATTN PHARMACIST: Empty contents of enclosed capsule into shampoo bottle.
  • Rx only
  • NDC
  • Capex
  • SHAMPOO (as dispensed)
  • 0.01%
  • For Topical Use OnlyShake Well Before UseDiscard Contents After Two Months
  • 4 fl oz
  • GALDERMA
  • ATTN PHARMACIST: Empty contents of enclosed capsule into shampoo bottle.
  • Usual Dose:n- no more than
  • See package insert for full prescribing information.
  • Marketed by:GALDERMA LABORATORIES, L.P.Fort Worth, Texas 76177 USA
  • Made in Canada.
  • All trademarks are the property of their respective owners.
  • P52307-3
  • Contains:
  • Storage:
  • Contents: 4 fl oz in 6 oz bottle for convenience of Pharmacist.
  • For External Use Only.
  • Keep out of reach of children.
  • Warning:

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