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Glipizide And Metformin Hydrochloride (Glipizide And Metformin Hydrochloride)

Trade Name : Glipizide and Metformin Hydrochloride

Teva Pharmaceuticals USA, Inc.

TABLET, FILM COATED

Strength 2.5250 mg/1mg/1

GLIPIZIDE; METFORMIN HYDROCHLORIDE Sulfonylurea [EPC],Sulfonylurea Compounds [CS],Biguanide [EPC],Biguanides [CS]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Glipizide And Metformin Hydrochloride (Glipizide And Metformin Hydrochloride) which is also known as Glipizide and Metformin Hydrochloride and Manufactured by Teva Pharmaceuticals USA, Inc.. It is available in strength of 2.5; 250 mg/1; mg/1 per ml. Read more

Glipizide And Metformin Hydrochloride (Glipizide And Metformin Hydrochloride) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • Glipizide and metformin hydrochloride tablets USP contain 2 oral antihyperglycemic drugs used in the management of type 2 diabetes, glipizide, USP and metformin hydrochloride, USP.
  • Glipizide, USP is an oral antihyperglycemic drug of the sulfonylurea class. The chemical name for glipizide, USP is 1-cyclohexyl-3-[[-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]urea. Glipizide, USP is a whitish, odorless powder with a pK of 5.9. It is insoluble in water and alcohols, but soluble in 0.1 NaOH; it is freely soluble in dimethylformamide. The structural formula is represented below.
  • CHNOS M.W. 445.55
  • Metformin hydrochloride, USP is an oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin hydrochloride, USP (,dimethylimidodicarbonimidic diamide monohydrochloride) is not chemically or pharmacologically related to sulfonylureas, thiazolidinediones, or u03b1-glucosidase inhibitors. It is a white to off-white crystalline compound. Metformin hydrochloride, USP is freely soluble in water and is practically insoluble in acetone, ether, and chloroform. The pK of metformin is 12.4. The pH of a 1% aqueous solution of metformin hydrochloride, USP is 6.68. The structural formula is as shown:
  • CHClN M.W. 165.63
  • Glipizide and metformin hydrochloride tablets USP for oral administration contain 2.5 mg glipizide, USP with 250 mg metformin hydrochloride, USP, 2.5 mg glipizide, USP with 500 mg metformin hydrochloride, USP, and 5 mg glipizide, USP with 500 mg metformin hydrochloride, USP. In addition, each tablet contains the following inactive ingredients: corn starch, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol-part. hydrolyzed, povidone, talc, and titanium dioxide. Additionally, 2.5 mg/250 mg and 5 mg/500 mg tablets contain iron oxide black, iron oxide red, and iron oxide yellow. The tablets are film-coated, which provides color differentiation.
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  • Glipizide and metformin hydrochloride tablets USP are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
  • Glipizide and metformin hydrochloride tablets are contraindicated in patients with:
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  • Glipizide and metformin hydrochloride tablets USP are available as follows:
  • 2.5 mg/250 mg are pink, film-coated, modified capsule-shaped tablets, debossed with u201c93u201d on one side and u201c7455u201d on the other in bottles of 100 (NDC 0093-7455-01).
  • 2.5 mg/500 mg are white, film-coated, modified capsule-shaped tablets, debossed with u201c93u201d on one side and u201c7456u201d on the other in bottles of 100 (NDC 0093-7456-01).
  • 5 mg/500 mg are pink, film-coated, modified capsule-shaped tablets, debossed with u201c93u201d on one side and u201c7457u201d on the other in bottles of 100 (NDC 0093-7457-01).
  • STORAGE
  • Store at 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F) [See USP Controlled Room Temperature].
  • Dispense in a tight, light-resistant container as defined in the USP, with a child-resistant closure (as required).
  • Manufactured In Israel By:
  • Teva Pharmaceutical Ind. Ltd.
  • Jerusalem, 9777402, Israel
  • Manufactured For:
  • Teva Pharmaceuticals USA, Inc.
  • North Wales, PA 19454
  • Rev. L 1/2017
  • Glipizide (GLIP-i-zide) and Metformin Hydrochloride (met-FOR-min hye-dro-KLOR-ide) Tablets USP
  • Rx only
  • Q1. Why do I need to take glipizide and metformin hydrochloride tablets?
  • Your doctor has prescribed glipizide and metformin hydrochloride tablets to treat your type 2 diabetes. This is also known as non-insulin-dependent diabetes mellitus.
  • Q2. What is type 2 diabetes?
  • People with diabetes are not able to make enough insulin and/or respond normally to the insulin their body does make. When this happens, sugar (glucose) builds up in the blood. This can lead to serious medical problems, including kidney damage, amputations, and blindness. Diabetes is also closely linked to heart disease. The main goal of treating diabetes is to lower your blood sugar to a normal level.
  • Q3. Why is it important to control type 2 diabetes?
  • The main goal of treating diabetes is to lower your blood sugar to a normal level. Studies have shown that good control of blood sugar may prevent or delay complications, such as heart disease, kidney disease, or blindness.
  • Q4. How is type 2 diabetes usually controlled?
  • High blood sugar can be lowered by diet and exercise, a number of oral medications, and insulin injections. Before taking glipizide and metformin hydrochloride tablets you should first try to control your diabetes by exercise and weight loss. Even if you are taking glipizide and metformin hydrochloride tablets, you should still exercise and follow the diet recommended for your diabetes.
  • Q5. Does glipizide and metformin hydrochloride tablets work differently from other glucose-control medications?
  • Yes, they do. Glipizide and metformin hydrochloride tablets combine 2 glucose-lowering drugs, glipizide and metformin. These 2 drugs work together to improve the different metabolic defects found in type 2 diabetes. Glipizide lowers blood sugar primarily by causing more of the bodyu2019s own insulin to be released, and metformin lowers blood sugar, in part, by helping your body use your own insulin more effectively. Together, they are efficient in helping you to achieve better glucose control.
  • Q6. What happens if my blood sugar is still too high?
  • When blood sugar cannot be lowered enough by glipizide and metformin hydrochloride tablets, your doctor may prescribe injectable insulin or take other measures to control your diabetes.
  • Q7. Can glipizide and metformin hydrochloride tablets cause side effects?
  • Glipizide and metformin hydrochloride tablets, like all blood sugar-lowering medications, can cause side effects in some patients. Most of these side effects are minor. However, there are also serious, but rare, side effects related to glipizide and metformin hydrochloride tablets (see ).
  • Q8. What are the most common side effects of glipizide and metformin hydrochloride tablets?
  • The most common side effects of glipizide and metformin hydrochloride tablets are normally minor ones such as diarrhea, nausea, and upset stomach. If these side effects occur, they usually occur during the first few weeks of therapy. Taking your glipizide and metformin hydrochloride tablets with meals can help reduce these side effects.
  • Symptoms of hypoglycemia (low blood sugar), such as lightheadedness, dizziness, shakiness, or hunger may occur. The risk of hypoglycemic symptoms increases when meals are skipped, too much alcohol is consumed, or heavy exercise occurs without enough food. Following the advice of your doctor can help you to avoid these symptoms.
  • Q9. Are there any serious side effects that glipizide and metformin hydrochloride tablets can cause?
  • People who have a condition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency and who take glipizide and metformin hydrochloride tablets may develop hemolytic anemia (fast breakdown of red blood cells). G6PD deficiency usually runs in families. Tell your doctor if you or any members of your family have been diagnosed with G6PD deficiency before you start taking glipizide and metformin hydrochloride tablets.
  • Glipizide and metformin hydrochloride tablets rarely cause serious side effects. n
  • Call your doctor right away if you have any of the following symptoms, which could be signs of lactic acidosis:
  • Most people who have had lactic acidosis with metformin have other things that, combined with the metformin, led to the lactic acidosis. Tell your doctor if you have any of the following, because you have a higher chance for getting lactic acidosis with glipizide and metformin tablets if you:
  • The best way to keep from having a problem with lactic acidosis from metformin is to tell your doctor if you have any of the problems in the list above. Your doctor may decide to stop your glipizide and metformin hydrochloride tablets for a while if you have any of these things.
  • Glipizide and metformin hydrochloride tablets can have other serious side effects. See u201cu201d
  • Q10. Can I take glipizide and metformin hydrochloride tablets with other medications?
  • Remind your doctor that you are taking glipizide and metformin hydrochloride tablets when any new drug is prescribed or a change is made in how you take a drug already prescribed.
  • Glipizide and metformin hydrochloride tablets may interfere with the way some drugs work and some drugs may interfere with the action of glipizide and metformin hydrochloride tablets.
  • Q11. What if I become pregnant while taking glipizide and metformin hydrochloride tablets?
  • Tell your doctor if you plan to become pregnant or have become pregnant. As with other oral glucose-control medications, you should not take glipizide and metformin hydrochloride tablets during pregnancy.
  • Usually your doctor will prescribe insulin while you are pregnant. As with all medications, you and your doctor should discuss the use of glipizide and metformin hydrochloride tablets if you are nursing a child.
  • Q12. How do I take glipizide and metformin hydrochloride tablets?
  • Your doctor will tell you how many glipizide and metformin hydrochloride tablets to take and how often.
  • This should also be printed on the label of your prescription. You will probably be started on a low dose of glipizide and metformin hydrochloride tablets and your dosage will be increased gradually until your blood sugar is controlled.
  • Q13. Where can I get more information about glipizide and metformin hydrochloride tablets?
  • This leaflet is a summary of the most important information about glipizide and metformin hydrochloride tablets.
  • If you have any questions or problems, you should talk to your doctor or other healthcare provider about type 2 diabetes as well as glipizide and metformin hydrochloride tablets and its side effects. There is also a leaflet (package insert) written for health professionals that your pharmacist can let you read.
  • All brand names listed are the registered trademarks of their respective owners and are not trademarks of Teva Pharmaceuticals USA, Inc.
  • Manufactured In Israel By:
  • TEVA PHARMACEUTICAL IND. LTD.
  • Jerusalem, 9777402, Israel
  • Manufactured For:
  • TEVA PHARMACEUTICALS USA, INC.
  • North Wales, PA 19454
  • Rev. E 4/2016
  • NDCn- 7455
  • Glipizide
  • and Metformin
  • Hydrochloride
  • Tablets USP
  • 2.5 mg/250 mg
  • PHARMACIST: PLEASE DISPENSE WITH
  • ATTACHED PATIENT INFORMATION LEAFLET
  • Rx only
  • 100 TABLETS
  • TEVA
  • Arrayn- Array
  • NDCn- 7456
  • Glipizide
  • and Metformin
  • Hydrochloride
  • Tablets USP
  • 2.5 mg/500 mg
  • PHARMACIST: PLEASE DISPENSE WITH
  • ATTACHED PATIENT INFORMATION LEAFLET
  • Rx only
  • 100 TABLETS
  • TEVA
  • Arrayn- Array
  • NDCn- 7457
  • Glipizide
  • and Metformin
  • Hydrochloride
  • Tablets USP
  • 5 mg/500 mg
  • PHARMACIST: PLEASE DISPENSE WITH
  • ATTACHED PATIENT INFORMATION LEAFLET
  • Rx only
  • 100 TABLETS
  • TEVA
  • Arrayn- Array

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