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Methylprednisolone Acetate (Depo-Medrol)

Trade Name : Depo-Medrol

Pharmacia and Upjohn Company LLC

INJECTION, SUSPENSION

Strength 20 mg/mL

METHYLPREDNISOLONE ACETATE Corticosteroid [EPC],Corticosteroid Hormone Receptor Agonists [MoA]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Methylprednisolone Acetate (Depo-Medrol) which is also known as Depo-Medrol and Manufactured by Pharmacia and Upjohn Company LLC. It is available in strength of 20 mg/mL per ml. Read more

Methylprednisolone Acetate (Depo-Medrol) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • NOT FOR USE IN NEONATESCONTAINS BENZYL ALCOHOL
  • Not For Intravenous Use
  • DEPO-MEDROL is an anti-inflammatory glucocorticoid for intramuscular, intra-articular, soft tissue, or intralesional injection. It is available in three strengths: 20 mg/mL, 40 mg/mL, 80 mg/mL.
  • Each mL of these preparations contains:
  • Sodium Chloride was added to adjust tonicity.
  • When necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid.
  • The pH of the finished product remains within the USP specified range (e.g., 3.5 to 7.0).
  • The chemical name for methylprednisolone acetate is pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-,(6u03b1,11u00df)- and the molecular weight is 416.51. The structural formula is represented below:
  • DEPO-MEDROL Sterile Aqueous Suspension contains methylprednisolone acetate which is the 6-methyl derivative of prednisolone. Methylprednisolone acetate is a white or practically white, odorless, crystalline powder which melts at about 215u00b0 with some decomposition. It is soluble in dioxane, sparingly soluble in acetone, alcohol, chloroform, and methanol, and slightly soluble in ether. It is practically insoluble in water.
  • Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids.
  • Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt retaining properties, are used in replacement therapy in adrenocortical deficiency states. Their synthetic analogs are used primarily for their anti-inflammatory effects in disorders of many organ systems.
  • Glucocorticoids cause profound and varied metabolic effects. In addition, they modify the body's immune response to diverse stimuli.
  • No data
  • DEPO-MEDROL is contraindicated in patients with known hypersensitivity to the product and its constituents.
  • Intramuscular corticosteroid preparations are contraindicated for idiopathic thrombocytopenic purpura.
  • DEPO-MEDROL Sterile Aqueous Suspension is contraindicated for intrathecal administration. Reports of severe medical events have been associated with this route of administration.
  • DEPO-MEDROL is contraindicated for use in premature infants because the formulation contains benzyl alcohol. (See and .)
  • DEPO-MEDROL is contraindicated in systemic fungal infections, except when administered as an intra-articular injection for localized joint conditions (see ).
  • No data
  • No data
  • The following adverse reactions have been reported with DEPO-MEDROL or other corticosteroids:
  • Arrayn- Allergic reactions
  • Arrayn- :
  • Cardiovascularn- Array
  • Dermatologic
  • Endocrine
  • Fluid and electrolyte disturbances
  • Gastrointestinal
  • Metabolic
  • Musculoskeletal
  • Neurologic/Psychiatric
  • Ophthalmic
  • Othern- Array
  • The following adverse reactions have been reported with the following routes of administration:
  • Intrathecal/Epidural
  • Intranasal
  • Ophthalmic
  • Miscellaneous injection sites
  • scalp, tonsillar fauces, sphenopalatine ganglion):
  • Treatment of acute overdosage is by supportive and symptomatic therapy. For chronic overdosage in the face of severe disease requiring continuous steroid therapy, the dosage of the corticosteroid may be reduced only temporarily, or alternate day treatment may be introduced.
  • NOTE: CONTAINS BENZYL ALCOHOL (n- Arrayn- Array
  • Because of possible physical incompatibilities, DEPO-MEDROL Sterile Aqueous Suspension should not be diluted or mixed with other solutions.
  • The initial dosage of parenterally administered DEPO-MEDROL will vary from 4 to 120 mg depending on the specific disease entity being treated. However, in certain overwhelming, acute, life-threatening situations, administration in dosages exceeding the usual dosages may be justified and may be in multiples of the oral dosages.
  • It Should Be Emphasized that Dosage Requirements Are Variable and Must Be Individualized on the Basis of the Disease Under Treatment and the Response of the Patient.
  • DEPO-MEDROL Sterile Aqueous Suspension is available in the following strengths and package sizes:
  • Store at controlled room temperature 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F) [see USP].
  • This product's label may have been updated. For current full prescribing information, please visit www.pfizer.com.
  • LAB-0159-13.0July 2018
  • 5 mL Multidose Vial
  • Depo-Medroln n- PREDNIS
  • 100 mg/5 mL
  • (20 mg/mL)Rx only
  • 5 mLMultidose Vial
  • NDC 0009-0274-01
  • Depo-Medroln n- PREDNIS
  • 100 mg/5 mL
  • (20 mg/mL)
  • For intramuscular,intrasynovial andsoft tissue injection only
  • NOT for IV use
  • Contains Benzyl Alcoholas a Preservative
  • Rx only
  • Pfizer Injectables
  • 5 mL Multidose Vial
  • Depo-Medroln n- PREDNIS
  • 200 mg/5 mL(40 mg/mL)
  • Rx only
  • 25u20145 mL Multidose Vials
  • NDC 0009-0280-51Contains 25 of NDC 0009-0280-02
  • Depo-Medroln- PREDNIS
  • 200 mg/5 mL(40 mg/mL)
  • For intramuscular, intrasynovial and soft tissue injection onlyNOT for IV usen n
  • Pfizer Injectables
  • Rx only
  • 5 mL Multidose Vial
  • Depo-Medroln n- PREDNIS
  • 400 mg/5 mL(80 mg/mL)
  • Rx only
  • 5 mLMultidose Vial
  • NDC 0009-0306-02
  • Depo-Medroln n- PREDNIS
  • 400 mg/5 mL(80 mg/mL)
  • For intramuscular,intrasynovial andsoft tissue injection only
  • NOT for IV use
  • Contains Benzyl Alcoholas a Preservative
  • Rx only
  • Pfizer Injectables

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