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Phenobarbital (Phenobarbital)

Trade Name : Phenobarbital

West-Ward Pharmaceuticals Corp

TABLET

Strength 60 mg/1

PHENOBARBITAL

Delivery Process

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Phenobarbital (Phenobarbital) which is also known as Phenobarbital and Manufactured by West-Ward Pharmaceuticals Corp. It is available in strength of 60 mg/1 per ml. Read more

Phenobarbital (Phenobarbital) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

Read more
  • No data
  • Phenobarbital is a barbituric acid derivative for oral administration and occurs as a white, odorless, slightly bitter powder that is soluble in chloroform, freely soluble in alcohol or ether, and slightly soluble in water. Its saturated solution has a pH of about 5.6. Chemically, it is 5-ethyl-5-phenylbarbituric acid with the molecular formula CHNO(232.24). The structural formula is as follows:
  • Each Phenobarbital Tablet USP contains 15 mg, 30 mg, 60 mg or 100 mg of phenobarbital, USP. n
  • Inactive Ingredients are as follows:
  • Anhydrous Lactose, Colloidal Silicon Dioxide, Corn Starch, Docusate Sodium with Sodium Benzoate, Lactose Monohydrate, Magnesium Stearate, Microcrystalline Cellulose, and Sodium Starch Glycolate.
  • Phenobarbital, a long-acting barbiturate, is a central nervous system depressant. In ordinary doses, the drug acts as a sedative and anticonvulsant. Its onset of action occurs within 30 minutes, and the duration of action ranges from 5 to 6 hours. It is detoxified in the liver.
  • Phenobarbital Tablets, USP are indicated for use as a sedative or anticonvulsant.
  • Phenobarbital is contraindicated in patients who are hypersensitive to barbiturates. In such patients, severe hepatic damage can occur from ordinary doses and is usually associated with dermatitis and involvement of parenchymatous organs. A personal or familial history of acute intermittent porphyria represents one of the few absolute contraindications to the use of barbiturates. Phenobarbital is also contraindicated in patients with marked impairment of liver function, or respiratory disease in which dyspnea or obstruction is evident. It should not be administered to persons with known previous addiction to the sedative/hypnotic group, since ordinary doses may be ineffectual and may contribute to further addiction.
  • In small doses, the barbiturates may increase the reaction to painful stimuli. Taken by themselves, the barbiturates cannot be relied upon to relieve pain or even to produce sedation or sleep in the presence of severe pain.
  • No data
  • The following adverse reactions have been reported:
  • Controlled Substance:
  • Prolonged, uninterrupted use of barbiturates (particularly the short-acting drugs), even in therapeutic doses, may result in psychic and physical dependence. Withdrawal symptoms due to physical dependence following chronic use of large doses of barbiturates may include delirium, convulsions, and death.
  • The signs and symptoms of barbiturate poisoning are referable especially to the central nervous system and the cardiovascular system. Moderate intoxication resembles alcoholic inebriation. In severe intoxication, the patient is comatose, the level of reflex activity conforming in a general way to the intensity of the central depression. The deep reflexes may persist for some time despite coexistent coma. The Babinski sign is often positive. The EEG may be of the u201cburst-suppressionu201d type, with brief periods of electrical silence. The pupils may be constricted and react to light, but late in the course of barbiturate poisoning they may show hypoxic paralytic dilatation. Respiration is affected early. Breathing may be either slow or rapid and shallow; Cheyne-Stokes rhythm may be present. Respiratory minute volume is diminished, and hypoxia and respiratory acidosis may develop. The blood pressure falls, owing partly to depression of medullary vasomotor centers; partly to a direct action of the drug on the myocardium, sympathetic ganglia, and vascular smooth muscle; partly to hypoxia.
  • The patient thus develops a typical shock syndrome, with a weak and rapid pulse, cold and clammy skin, and a rise in the hematocrit. Respiratory complications (atelectasis, pulmonary edema, and bronchopneumonia) and renal failure are much dreaded and not infrequent concomitant of severe barbiturate poisoning. There is usually hypothermia, sometimes with temperatures as low as 32u00b0C.
  • General management should consist of symptomatic and supportive therapy, including gastric lavage, administration of intravenous fluids, and maintenance of blood pressure, body temperature and adequate respiratory exchange. Dialysis will increase the rate of removal of barbiturates from the body fluids. Antibiotics may be required to control pulmonary complications.
  • Oral Sedative Dose
  • Adults:
  • Children:
  • Oral Hypnotic Dose
  • Adults:
  • Oral Anticonvulsant Dose,
  • Adults:
  • Children:
  • Phenobarbital Tablets, USP 15 mg
  • u00a0White, Round Tablet; Debossed u201cWW 445u201d on one side and plain on the other side.
  • u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0NDC 0143-1495-01:u00a0Bottle of 100 tabletsu00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0NDC 0143-1495-05: Bottle of 500 tablets n
  • Phenobarbital Tablets, USP 30 mg
  • White, Round, Scored Tablet; Debossed u201cWW 450u201d on one side and Scored on the other side.
  • u00a0u00a0u00a0u00a0u00a0 u00a0u00a0u00a0u00a0 u00a0u00a0NDC 0143-1500-01:u00a0Bottle of 100 tabletsu00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0 u00a0u00a0u00a0u00a0 u00a0 NDC 0143-1500-05: Bottle of 500 tablets u00a0
  • Phenobarbital Tablets, USP 60 mg
  • White, Round Tablet; Debossed u201cWW 455u201d on one side and plain on the other side.
  • u00a0u00a0u00a0u00a0u00a0u00a0u00a0 u00a0u00a0u00a0u00a0 NDC 0143-1455-01:u00a0Bottle of 100 tabletsu00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0 u00a0u00a0u00a0u00a0 NDC 0143-1455-05: Bottle of 500 tablets
  • Phenobarbital Tablets, USP 100 mg
  • White, Round, Scored Tablet; Debossed u201cWW 458u201d on one side and Scored on the other side.
  • u00a0u00a0u00a0u00a0u00a0u00a0u00a0 u00a0u00a0u00a0u00a0 NDC 0143-1458-01: Bottle of 100 tabletsu00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0u00a0 u00a0u00a0u00a0u00a0 NDC 0143-1458-05: Bottle of 500 tablets
  • Store at 20u00b0 to 25u00b0C (68u00b0 to 77u00b0F) [See USP Controlled Room Temperature]. Protect from light and moisture.
  • Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.
  • Distr. by:n Eatontown, NJ 07724n
  • C50000803/01u00a0u00a0u00a0u00a0u00a0 Revisedu00a0July 2019
  • NDC 0143-1495-01Phenobarbital Tabletsu00a0USPu00a015 mg100 TabletsRx Only
  • NDC 0143-1500-01Phenobarbital Tabletsu00a0USPu00a0 30 mg100 TabletsRx Only
  • NDC 0143-1455-01Phenobarbital Tabletsu00a0USPu00a0 60 mg100 TabletsRx Only
  • NDC 0143-1458-01Phenobarbital Tabletsu00a0USPu00a0100 mg100 TabletsRx Only

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