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Pregabalin (Lyrica Cr)

Trade Name : Lyrica CR

Parke-Davis Div of Pfizer Inc

TABLET, FILM COATED, EXTENDED RELEASE

Strength 82.5 mg/1

PREGABALIN

Delivery Process

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Product information is meant for

Wholesalers Suppliers Exporters Doctors MOH Tender Supplies Hospitals Brand CROs Comparator Supplies Generic Cooperate Sourcing Individual Patients Indian Institutional Buyers

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Pregabalin (Lyrica Cr) which is also known as Lyrica CR and Manufactured by Parke-Davis Div of Pfizer Inc. It is available in strength of 82.5 mg/1 per ml. Read more

Pregabalin (Lyrica Cr) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

Read more
  • No data
  • No data
  • LYRICA CR is indicated for the management of:
  • Efficacy of LYRICA CR has not been established for the management of fibromyalgia or as adjunctive therapy for adult patients with partial onset seizures.
  • LYRICA CR is indicated for the management of:
  • Efficacy of LYRICA CR has not been established for the management of fibromyalgia or as adjunctive therapy for adult patients with partial onset seizures.
  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN) ()
  • Postherpetic neuralgia (PHN) ()
  • No data
  • Extended-release tablets: 82.5 mg, 165 mg, and 330 mg . tttttt
  • Extended-release tablets: 82.5 mg, 165 mg, and 330 mg. ()
  • LYRICA CR is contraindicated in patients with known hypersensitivity to pregabalin or any of its components. Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy .
  • Known hypersensitivity to pregabalin or any of its components. ()
  • No data
  • Angioedema
  • Hypersensitivity reactions
  • Suicidal Behavior and Ideation
  • Peripheral Edema
  • Dizziness and Somnolence
  • Increased seizure frequency may occur in patients with seizure disorders if LYRICA CR is rapidly discontinued. Withdraw LYRICA CR gradually over a minimum of 1 week. ()
  • The following adverse reactions are described elsewhere in the labeling:
  • Most common adverse reactions reported in greater than or equal to 4% of patients treated with LYRICA CR are dizziness, somnolence, headache, fatigue, peripheral edema, nausea, blurred vision, dry mouth, and weight gain. ()
  • To report SUSPECTED ADVERSE REACTIONS, contact Pfizer, Inc. at (800) 438-1985 or FDA at 1-800-FDA-1088 or .
  • Since pregabalin is predominantly excreted unchanged in the urine, undergoes negligible metabolism in humans (less than 2% of a dose recovered in urine as metabolites), and does not bind to plasma proteins, its pharmacokinetics are unlikely to be affected by other agents through metabolic interactions or protein binding displacement. studies showed that pregabalin is unlikely to be involved in significant pharmacokinetic drug interactions .
  • The interactions of LYRICA CR with co-administration of other drugs have not been systematically evaluated. Co-administration of the prokinetic drug erythromycin with LYRICA CR did not result in any clinically important changes in the pharmacokinetics of LYRICA CR .
  • Additional studies have been performed with LYRICA. No pharmacokinetic interactions were observed between LYRICA and carbamazepine, gabapentin, lamotrigine, oral contraceptive, phenobarbital, phenytoin, topiramate, and valproic acid. A similar lack of pharmacokinetic interactions would be expected to occur with LYRICA CR.
  • Pharmacodynamics
  • Although no pharmacokinetic interactions were seen, with LYRICA and ethanol, lorazepam, or oxycodone, additive effects on cognitive and gross motor functioning were seen when LYRICA was co-administered with these drugs. No clinically important effects on respiration were seen in studies of LYRICA.
  • No data
  • Pregnancy: May cause fetal harm. Advise of potential risk to the fetus. ()
  • Lactation: Breastfeeding is not recommended. ()
  • No data
  • No data
  • LYRICA CR (pregabalin extended-release) tablets are for oral use and contain pregabalin. Pregabalin is described chemically as ()-3-(aminomethyl)-5-methylhexanoic acid. The molecular formula is CHNO and the molecular weight is 159.23. The chemical structure of pregabalin is:
  • Pregabalin is a white to off-white, crystalline solid with a pK of 4.2 and a pK of 10.6. It is freely soluble in water and both basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is u2013 1.35.
  • LYRICA CR extended-release tablets are administered orally and contain 82.5, 165, or 330 mg of pregabalin, along with Kollidon SR (polyvinyl acetate, povidone, sodium lauryl sulphate, and silica), crospovidone, polyethylene oxide, carbomer, magnesium stearate, polyvinyl alcohol, titanium dioxide, talc, polyethylene glycol, and colorants as inactive ingredients.
  • No data
  • No data
  • No data
  • LYRICA CR is supplied in the following strengths and package configurations:
  • Store at 20u00b0C to 25u00b0C (68u00b0F to 77u00b0F), excursions permitted between 15u00b0C and 30u00b0C (between 59u00b0F and 86u00b0F) in the original package. (See USP Controlled Room Temperature)
  • Advise the patient to read the FDA-approved patient labeling (Medication Guide).
  • This product's label may have been updated. For current full prescribing information, please visit www.pfizer.com.
  • LAB-0769-2.0
  • No data
  • Pfizer
  • Lyrica CR
  • CV
  • 82.5 mg
  • ALWAYS DISPENSE WITHMEDICATION GUIDE
  • 30 Tabletsn n
  • Pfizer
  • Lyrica CR
  • CV
  • 165 mg
  • ALWAYS DISPENSE WITHMEDICATION GUIDE
  • 30 Tabletsn n
  • Pfizer
  • Lyrica CR
  • CV
  • 330 mg
  • ALWAYS DISPENSE WITHMEDICATION GUIDE
  • 30 Tabletsn n

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Comparator Sourcing for Clinical Trials

Comparator Sourcing for Clinical Trials

GNH India brings over 10 years of experience in Comparator

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Name Patient Supply

Name Patient Supply

Today, the exact cause for many rare diseases remains unknown

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Validated Cold Chain Shipment

Validated Cold Chain Shipment

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Clinical Trials Supply

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Pharmaceutical Contract Manufacturing

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